Follow this author to personalize your feed and get instant alerts. Follow Go to your personalized feed WHY FOLLOW? Smart Alerts: Get notified about major news as it happens. Only one in five women know that they're more likely to develop Alzheimer's disease than men, according to a recent survey. Maria Shriver wants that number to climb--and for women to start thinking about their brains decades before symptoms show up.

This actor was told he had Alzheimer's, now he's performing a one-man show Image caption, Peter Marinker, who was diagnosed with Alzheimer's disease two years ago, began dress rehearsals for the Beckett play Krapp's Last Tape in June For four days running, Peter Marinker had arrived at rehearsals that were not even taking place. Dementia had muddled the dates in his mind. Yet he is now preparing to do something most actors would find daunting even with perfect recall: performing a much-loved Samuel Beckett play alone on a London stage. Marinker, 85, is best known for his voice work: from radio plays and video games to big-budget films like Labyrinth and Paddington in Peru. On camera he was the adviser to the US president in Love Actually and one of the airline passengers in the drama United 93.

Follow this author to personalize your feed and get instant alerts. Follow Go to your personalized feed WHY FOLLOW? Smart Alerts: Get notified about major news as it happens. It seems odd that your body's internal age may differ from your chronological one. But Tony Wyss-Coray, a Swiss professor of neurology and director of the Knight Initiative for Brain Resilience at Stanford University, has pioneered ways to measure a person's "biological age," which scientists say more accurately reflects how a body is aging than does chronological age.

You're viewing the US edition You can switch to the UK or AU homepage at any time using this menu. US Army U-turn over futuristic drone and robot unit is slammed as'deeply dangerous' This is an epic humiliation for Harry and Meghan. But these two are dangerous... we should fear the twisted real strategy behind their UK return: MAUREEN CALLAHAN America's pancreatic cancer explosion: Science breakthrough leaves experts fearing surprisingly common lifestyle habit is behind surge in young patients... as new early warning sign is revealed Trump's under-siege aide Natalie Harp caught in foul-mouthed explosion as insiders reveal White House whispers about her close access to president Sussexes'already have a house lined up to live in... and it's not a Royal residence' A close friend of Trump has told me the truth about his young aide Natalie. There's a reason the whispers are getting louder: KENNEDY Hayden Panettiere's LA neighbors were warned to call police if they saw her ex Brian Hickerson in the past... as DEA reportedly joins investigation into star's death I was mocked a year ago when I warned there was an Establishment plot to bring Harry and Meghan back to Britain. Now I've been proven right... and my sources have made it clear this is only the beginning: RICHARD EDEN Surrogate who refused to abort baby in fresh battle with biological parents over child's NAME Why loyal Trump aide Natalie Harp has only one pair of shoes - and she can even drive a golf cart in them! The'affair mode' phone settings that all cheaters use: I knew my partner was up to something... here's how I cracked his secret code and uncovered all his dirty antics Read Brian Hickerson's sinister texts to girlfriend Hayden Panettiere as he breaks cover after star's death: 'Time to go to war' Shocking moment 16-year-old girl storms field and tackles middle school football player... before being hit with assault charges and lifetime ban Virginia mother stabbed to death on jogging trail'by teenage migrant coworker' who was caught entering US illegally two years ago... then released Brooklyn Beckham's pizza-making post is flooded with pleas from fans as he shares cooking video hours after brother Romeo attended Italian culinary class Common brain disorder suffered by millions is often dismissed as being'all in your head' READ MORE: Life skill that reduces chances of dying from Alzheimer's disease By the time many people with functional neurological disorder - a condition in which there is a problem with how the brain sends and receives signals - arrive at a doctor's office, they have heard these five words more times than they can count.

Researchers found that a metabolite produced by gut bacteria can weaken the barrier that protects the brain and promote changes associated with the cognitive disease. For years, scientists have known that the gut microbiome of people with Alzheimer's differs from that of healthy people. What remains unclear is whether these differences are a consequence of the disease, contribute to it, or simply accompany it. It is possible that part of the puzzle lies not in the gut bacteria themselves but in the molecules they produce, which end up circulating throughout the body. A team of scientists believes it has found one such molecule.

Follow this section to personalize your feed and get instant alerts. Follow Go to your personalized feed WHY FOLLOW? Smart Alerts: Get notified about major news as it happens. Alzheimer's Disease Open follow modal Personalized Content Follow this tag to personalize your feed and get instant alerts. Follow Go to your personalized feed WHY FOLLOW?

How healthy is your brain? In our efforts to keep our brains healthy, how do we know what is working? It shouldn't have been difficult: 72 x 72. From the back seat, my daughter, newly confident in mental maths, wanted to check her answer. Whether it was because it was the end of the day, I was trying to park or something else, I stalled, cognitively speaking. Lately, though, I have had the sense that my brain isn't firing on all cylinders.

A large-scale clinical trial has shown that even long-term consumption of DHA--an omega-3 fatty acid found in abundance in oily fish--may not lead to improvements in cognitive function. Docosahexaenoic acid (DHA), an omega-3 fatty acid found in abundance in oily fish such as mackerel and sardines, is thought to improve cognitive function by supporting connections between brain cells. However, it has never been conclusively demonstrated that DHA taken as a dietary supplement actually reaches the brain or provides measurable benefits against dementia . Against this backdrop, a research team at the USC School of Medicine has published the results of a large, two-year clinical trial involving older adults at elevated risk of developing Alzheimer's disease . The study found that while high-dose DHA supplements do indeed reach the brain, they did not improve memory or cognitive function, nor did they slow brain atrophy.

Medical time-series data play a vital role in disease diagnosis but suffer from limited labeled samples and single-center bias, which hinder model generalization and lead to overfitting. To address these challenges, we propose DAAC (Discrepancy-Aware Adaptive Contrastive learning), a learnable multi-view contrastive framework that integrates external normal samples and enhances feature learning through adaptive contrastive strategies. DAAC consists of two key modules: (1) a Discrepancy Estimator, built upon a GAN-enhanced encoder-decoder architecture, captures the distribution of normal data and computes reconstruction errors as indicators of abnormality. These discrepancy features augment the target dataset to mitigate overfitting.

BrainODElearns a deformation space over anatomically meaningful brain regions to facilitate early prediction of neurodegenerative disease progression. Addressing inherent challenges of longitudinal neuroimaging data--such as limited sample sizes, irregular temporal sampling, and substantial inter-subject variability--we propose a conditional neural ODE architecture that models shape dynamics with subject-specific age and cognitive status. To enable autoregressive forecasting of brain morphology from a single observation, we propose a pseudo-cognitive status embedding that allows progressive shape prediction across intermediate time points with predicted cognitive decline. Experiments show that BrainODE outperforms time-aware baselines in predicting future brain shapes, demonstrating strong generalization across longitudinal datasets with both regular and irregular time intervals.